Two new chromones from Portulaca oleracea L. and their bioactivities
Zheming Ying1, Kaiyun Jiang1, Jing Liu2
1School of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, P.R. China.
None:
Two new chromones, oleracone H (1) and oleracone I (2), were isolated from Portulaca oleracea L. and identified by UV, IR, UHPLC-ESI-QTOF/MS, 1D NMR, 2D NMR, and CD spectra. In 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, oleracone H (1) and oleracone I (2) presented scavenging activities with IC50 values (half maximal inhibitory concentration) of 16.33 ± 0.20 μM and 22.36 ± 0.41 μM and the abilities of inhibiting the inflammatory factors IL-1β and TNF-α of the two compounds were superior to that of the positive control at 10 μM.
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