Related Experiment Video
Updated: May 7, 2025

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
Published on: January 31, 2022
Developing Benchmarking Metrics for Appropriate Ordering of Vitamin D, Thyroid Testing, and Iron Workups
Hsuan-Chieh Liao1, Alec Saitman2, Jane Dickerson1,3
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Laboratory stewardship programs can be improved using benchmarking metrics. These metrics help labs compare test utilization, like vitamin D and thyroid testing, to enhance patient care and resource use.
Area of Science:
- Clinical Laboratory Science
- Healthcare Management
- Health Informatics
Background:
- Laboratory stewardship programs aim to optimize test utilization and patient care.
- Implementation in complex healthcare systems faces challenges.
- Benchmarking metrics are underutilized in laboratory stewardship literature.
Purpose of the Study:
- To develop and pilot benchmarking metrics for laboratory stewardship.
- To address common test utilization issues using easily calculable data.
- To establish optimal benchmarks through inter-laboratory comparisons.
Main Methods:
- The PLUGS Informatics Working Group developed guidelines and metrics.
- Pilot study focused on vitamin D, thyroid, and iron workup test orders.
- Institutions analyzed their own data against established benchmarks.
Main Results:
- Established benchmarks: 50:1 for vitamin D (25-hydroxyvitamin D to 1,25-dihydroxyvitamin D), 3.5:1 for thyroid (TSH to FT4), and 50% for iron workup.
- Nine labs evaluated vitamin D, nine thyroid, and seven iron workups.
- Intervention guidelines were provided for labs below benchmarks.
Conclusions:
- Benchmarking metrics offer a standardized approach to assess and improve test utilization.
- Refinement of benchmarking methodologies is crucial for maximizing stewardship program impact.
- Enhanced laboratory stewardship improves patient safety and resource utilization.
More Related Videos
09:58Quantitative Immunoblotting of Cell Lines as a Standard to Validate Immunofluorescence for Quantifying Biomarker Proteins in Routine Tissue Samples
Published on: January 7, 2019
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Related Concept Videos
Serum Laboratory Studies, Stool Test, Breath Test
Guidelines For Measuring Vital Signs
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...