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Noncontraceptive estrogens and progestins: use patterns over time.

D L Kennedy, C Baum, M B Forbes

    Obstetrics and Gynecology
    |March 1, 1985
    PubMed
    Summary
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    Noncontraceptive estrogens and progestins, used by menopausal women, show increasing trends from 1966-1983. Usage in 1983 involved lower estrogen doses and combined therapies, treating millions daily.

    Area of Science:

    • Pharmacology
    • Endocrinology
    • Women's Health

    Background:

    • Noncontraceptive hormone use, particularly estrogens and progestins, has been controversial.
    • Hormone therapy is frequently prescribed for menopausal symptom management.

    Purpose of the Study:

    • To review overall trends in noncontraceptive estrogen and progestin use from 1966 to 1983.
    • To provide a detailed description of their usage patterns in 1983.

    Main Methods:

    • Retrospective analysis of drug usage data.
    • Review of prescription trends for oral estrogens and progestins.

    Main Results:

    • Overall use of noncontraceptive estrogens and progestins has been increasing.
    • In 1983, estrogen doses were lower than in previous years.

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  • A trend towards concomitant use of both estrogens and progestins was observed.

    • Conclusions:

    • Noncontraceptive hormone therapy use is rising again.
    • Current prescribing patterns favor lower estrogen doses and combination therapy.
    • Significant daily populations were treated with oral estrogens and progestins in 1983.