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[Pseudomonas pickettii septicemia].

M Chomarat, A Lepape, J Y Riou

    Pathologie-Biologie
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

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    This case report details a Pseudomonas pickettii bacteremia in a diabetic patient. Doxycycline effectively treated the infection after cefotaxime failed, despite in vitro susceptibility.

    Area of Science:

    • Medical Microbiology
    • Infectious Diseases
    • Clinical Bacteriology

    Background:

    • Pseudomonas pickettii is an opportunistic pathogen that can cause serious infections, particularly in immunocompromised individuals.
    • Bacteremia in diabetic patients presents unique challenges due to altered immune function and potential complications.

    Observation:

    • A case of bacteremia caused by Pseudomonas pickettii in a patient with insulin-dependent diabetes mellitus is presented.
    • The portal of entry for the infection remained unidentified.
    • The patient initially received cefotaxime, an antibiotic to which the Pseudomonas pickettii strain demonstrated susceptibility via disk assay.

    Findings:

    • Cefotaxime therapy proved ineffective in resolving the bacteremia and associated fever.

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  • Subsequent treatment with doxycycline resulted in the patient becoming afebrile, indicating successful eradication of the infection.
  • This highlights a potential discrepancy between in vitro antibiotic susceptibility and clinical treatment outcomes.

    • Implications:

    • This case underscores the importance of considering alternative treatment strategies when initial antibiotic therapy fails, even with demonstrated in vitro susceptibility.
    • Pseudomonas pickettii bacteremia requires careful management, especially in diabetic patients.
    • Further investigation into treatment failures and alternative therapies for Pseudomonas pickettii infections is warranted.