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Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
A Review on Integrating Breast Cancer Clinical Data: A Unified Platform Perspective
Ram Mohan Ram Kumar1, Suresh Joghee2
1Department of Pharmaceutical Biotechnology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India. rammohanramkumar@jssuni.edu.in.
Integrating diverse clinical datasets in breast cancer research is crucial for advancing knowledge and improving patient care. This approach enhances understanding of disease complexity and treatment responses, paving the way for precision medicine.
Area of Science:
- Oncology
- Medical Informatics
- Data Science
Background:
- Clinical dataset integration is essential for advancing breast cancer research and patient outcomes.
- Synthesizing diverse datasets offers benefits for evidence-based insights, predictive analytics, and precision medicine.
Purpose of the Study:
- To review the imperative and benefits of integrating clinical datasets in breast cancer research.
- To highlight the need for collaborative efforts, policy changes, and technological advancements in breast cancer data management.
Main Methods:
- This narrative review synthesizes current literature on clinical dataset integration in breast cancer.
Main Results:
- Integrating diverse datasets (demographics, tumor characteristics, treatments, outcomes) enhances understanding of disease complexity and treatment responses across populations.
- Conditional regulatory approval for new treatments based on real-world evidence is proposed.
- Incorporating high-quality real-world evidence into treatment guidelines is crucial for patient counseling and personalized strategies.
Conclusions:
- Dataset integration is vital for advancing breast cancer research, optimizing patient management, and enabling precision medicine.
- Policy and technological advancements are necessary to establish global standards for breast cancer data integration and care.
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