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Related Concept Videos

Epistasis01:39

Epistasis

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In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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Background and Environment Affect Phenotype02:27

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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
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Epistasis Analysis01:09

Epistasis Analysis

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Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
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Monohybrid Crosses01:20

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Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Related Experiment Video

Updated: Jun 4, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Ginger genes: decoding the cause of the colouring.

Arabella Gray

    The Veterinary Record
    |January 3, 2025
    PubMed
    Summary

    Two new studies reveal the genetic basis for the orange coat color in domestic cats. This research uncovers key genes influencing feline coat pigmentation and orange coloration patterns.

    Area of Science:

    • Genetics
    • Animal Biology
    • Coat Color Genetics

    Background:

    • The genetic mechanisms underlying feline coat color variation are complex.
    • Orange coloration in cats is a widely observed but not fully understood phenotype.

    Discussion:

    • Two recent studies converge to elucidate the genetic underpinnings of orange coat color in cats.
    • These findings shed light on the specific genes and mutations responsible for this common feline trait.

    Key Insights:

    • The research identifies specific genetic loci associated with orange pigment production.
    • Understanding these genes provides a foundation for further studies in feline coat color genetics.

    Outlook:

    • Future research can explore the evolutionary significance of these genes in cat populations.

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  • This work may inform breeding practices and the study of other animal coat colorations.