ANTERIOR UVEITIS, PIGMENTARY RETINOPATHY, AND PARS PLANA EXUDATES IN CELIAC DISEASE

Area of Science:

• Ophthalmology
• Gastroenterology
• Immunology

Background:

• Celiac disease is an autoimmune disorder triggered by gluten.
• Ocular manifestations of celiac disease are rare but can be severe.
• Uveitis, pigmentary retinopathy, and pars plana exudates are potential ocular findings.

Purpose of the Study:

• To present a case of bilateral uveitis, pigmentary retinopathy, and pars plana exudates.
• To investigate the link between Celiac disease and these ocular conditions.
• To demonstrate the efficacy of a gluten-free diet in managing ocular inflammation associated with Celiac disease.

Main Methods:

• Retrospective case report.
• Clinical examination of ocular findings.
• Laboratory investigations including antibody testing and biopsy.
• Monitoring of ocular inflammation following dietary intervention.

Main Results:

• A 19-year-old patient presented with bilateral anterior uveitis, pigmentary retinopathy, and pars plana exudates.
• Diagnosis of Celiac disease was confirmed via antibody testing and duodenal biopsy.
• Complete resolution of ocular inflammation was achieved after initiating a gluten-free diet.

Conclusions:

• Celiac disease is an uncommon cause of corticosteroid-resistant uveitis.
• Ocular manifestations of Celiac disease can be diverse and may resolve with dietary changes.
• Early diagnosis and gluten-free diet are crucial for managing Celiac disease-associated uveitis.