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Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
ANTERIOR UVEITIS, PIGMENTARY RETINOPATHY, AND PARS PLANA EXUDATES IN CELIAC DISEASE
Aniruddha Agarwal1,2, Surinder S Rana3, Kirti Gupta4
1The Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates (UAE).
Purpose:
The objective of this study was to report a case of bilateral anterior uveitis, pigmentary retinopathy, and pars plana exudates in a patient with celiac disease with complete resolution of inflammation following gluten-free diet.
Methods:
This was a retrospective case report.
Results:
A 19-year-old Asian Indian woman presented with bilateral nongranulomatous anterior uveitis for the past 2 months. Examination revealed bilateral pigmentary retinopathy and exudates near the inferior pars plana in the left eye. Laboratory evaluation revealed positive antitissue transglutaminase antibody, low thyroid stimulating hormone, low serum ferritin, anemia, and vitamin D deficiency. Her duodenal biopsy was confirmatory for celiac disease. After initiation of gluten-free diet, there was complete resolution of anterior segment inflammation and vitreous exudates.
Conclusion:
Celiac disease is a rare cause of corticosteroid-resistant uveitis with a handful of cases reported in the literature. This condition has protean manifestations and resolves with gluten-free diet.
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