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Updated: Jul 15, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS IN SYPHILITIC OUTER RETINITIS
Luis Zeman1, Mauricio Martínez Cartier2, Cristóbal Couto3
1Instituto Zeman Bardeci, Salta, Argentina.
Purpose:
The objective of this study was to report optical coherence tomography angiography findings in syphilitic outer retinopathy, a singular clinical manifestation of ocular syphilis.
Methods:
This was a case report.
Results:
Multimodal imaging including optical coherence tomography angiography was performed in a patient presenting syphilitic outer retinopathy. Optical coherence tomography angiography showed multifocal areas of flow deficit at the choriocapillaris level at presentation, whereas no vascular abnormalities were observed at deep and superficial capillary plexuses. After a 1-year follow-up period, choriocapillaris flow showed an almost complete recovery.
Conclusion:
Syphilitic outer retinopathy represents a singular clinical manifestation of ocular syphilis. The almost complete recovery of initial ischemic changes at 1 year of follow-up suggests that this entity may have a good prognosis with timely and proper antibiotic treatment.
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