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Updated: Jul 6, 2026

A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation VCA Research
Published on: October 14, 2013
Engineered hiPSC-derived vascular graft brings hope for thrombosis-free vascular therapy
Soniya Tamhankar1, Eric V Shusta2, Sean P Palecek1
1Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Abstract:
Tissue-engineered vascular conduits (TEVCs) are a promising blood vessel replacement. In a recent publication in Cell Stem Cell,1 Park et al. developed TEVCs comprised of decellularized human umbilical arteries lined with shear-trained, human induced pluripotent stem cell (hiPSC)-derived endothelial cells (ECs) that resisted thrombosis and exhibited patency upon grafting into the rat inferior vena cava (IVC).

