Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of Myofascial Release Therapy and Related Soft-Tissue Techniques for Pain in Temporomandibular Disorders: A Systematic Review of Randomized Controlled Trials.

Journal of oral rehabilitation·2026
Same author

Plastic deformation evaluation of clear aligners exposed to different cleaning solutions.

The Angle orthodontist·2026
Same author

Ten-Year Post-Loading Outcomes of Subcrestally Placed Implants With Internal Conical Connections at 0.5 mm Versus 1.5 mm Depth: A Multicentre Within-Person Randomised Controlled Trial.

Clinical oral implants research·2026
Same author

Development of an AI-based model for sex estimation using CT-derived metrics from paranasal sinuses.

International journal of legal medicine·2026
Same author

Early-Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·2026
Same author

Automated artificial intelligence-driven 3-dimensional craniofacial superimposition for clinically useful treatment outcomes in growing patients: A multicenter study.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics·2026

Related Experiment Video

Updated: Jun 16, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.5K

Deep Learning-Based Three-Dimensional Analysis Reveals Distinct Patterns of Condylar Remodelling After Orthognathic

Selene Barone1, Lucia Cevidanes2, Jonas Bianchi3

  • 1Department of Health Sciences, School of Dentistry, Magna Graecia University of Catanzaro, Catanzaro, Italy.

Orthodontics & Craniofacial Research
|January 4, 2025
PubMed
Summary

Virtual surgical planning and deep learning analysis showed minimal overall condylar changes after two-jaw orthognathic surgery for skeletal Class III malocclusion, with significant regional bone remodelling correlated to condylar displacement.

Keywords:
condylar morphologycondylar remodellingdeep learning‐based 3D analysisorthognathic surgeryskeletal class III

More Related Videos

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

7.3K
Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures
09:10

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

1.7K

Related Experiment Videos

Last Updated: Jun 16, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.5K
Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

7.3K
Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures
09:10

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

1.7K

Area of Science:

  • Orthodontics and Maxillofacial Surgery
  • Medical Imaging Analysis
  • Artificial Intelligence in Healthcare

Background:

  • Skeletal Class III malocclusion often requires orthognathic surgery for correction.
  • Virtual surgical planning (VSP) and advanced imaging analysis are increasingly used in complex surgical cases.
  • Understanding mandibular condyle morphometric changes post-surgery is crucial for long-term stability.

Purpose of the Study:

  • To evaluate morphometric changes in mandibular condyles after two-jaw orthognathic surgery.
  • To assess the impact of virtual surgical planning (VSP) on condylar remodelling.
  • To analyze surgical outcomes using automated 3D image analysis with deep learning.

Main Methods:

  • Retrospective analysis of Cone-Beam Computed Tomography (CBCT) scans from 17 skeletal Class III patients.
  • Automated 3D image analysis using deep learning for CBCT orientation, segmentation, and landmark identification.
  • Voxel-based superimposition to assess bone resorption and apposition on condylar surfaces and correlate with condylar displacement.

Main Results:

  • Overall condylar remodelling was minimal (<1 mm).
  • Statistically significant bone resorption occurred at the superior articular surface.
  • Bone apposition was observed at the lateral pole, correlated with medial condylar displacement (p<0.05).

Conclusions:

  • Automated 3D analysis reveals distinct regional condylar remodelling patterns post-orthognathic surgery in Class III patients.
  • Minimal overall changes mask significant regional variations in bone resorption and apposition.
  • Precise pre-operative planning is essential to optimize condylar positioning and minimize adverse remodelling for enhanced stability.