Related Experiment Video

Updated: Aug 8, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
10:50

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 16, 2010

Dynamics and conformational energetics of a peptide hormone: vasopressin

A T Hagler, D J Osguthorpe, P Dauber-Osguthorpe

    Science (New York, N.Y.)
    |March 15, 1985
    PubMed

    More Related Videos

    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR14:44

    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

    Published on: December 16, 2013

    Study of Protein Dynamics via Neutron Spin Echo Spectroscopy08:03

    Study of Protein Dynamics via Neutron Spin Echo Spectroscopy

    Published on: April 13, 2022

    Related Concept Videos

    Protein Folding01:22

    Protein Folding

    Overview
    Overview of Secretory Vesicles01:33

    Overview of Secretory Vesicles

    Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
    Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
    Energy to Drive Translocation01:37

    Energy to Drive Translocation

    Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
    Generally, polypeptides are unfolded by two distinct...
    ATP Driven Pumps III: V-type Pumps01:30

    ATP Driven Pumps III: V-type Pumps

    V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
    The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
    Protein Folding01:25

    Protein Folding

    Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
    Protein Structure Is Critical to Its Biological Function
    Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
    Transducer Mechanism: Enzyme-Linked Receptors01:27

    Transducer Mechanism: Enzyme-Linked Receptors

    Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
    Major types that are helpful drug targets include: