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Updated: Jun 4, 2025

Transcranial Direct Current Stimulation for Online Gamers
Published on: November 9, 2019
The hemispheric differences in prefrontal function of Internet game disorder and non-Internet game disorder: an
Rui Xue1,2, Jiaqi Li1,2, Haibo Yang1,2,3
1Key Research Base of Humanities and Social Sciences of the Ministry of Education, Academy of Psychology and Behavior, Tianjin Normal University, No. 393 Binshuixi Road, Xiqing District, Tianjin 300387, China.
Abstract:
This study explored the differences in brain activation between individuals with and without Internet gaming disorder (IGD) through activation likelihood estimation analysis. In total, 39 studies were included based on the inclusion and exclusion criteria by searching the literature in the PubMed and Web of Science databases, as well as reading other reviews. The analysis revealed that the activated brain regions in IGD were the right inferior frontal gyrus, left cingulate gyrus, and left lentiform nucleus. In comparison, the activated brain regions in non-IGD were the left middle frontal, left inferior frontal, left anterior cingulate, left precentral, and right precentral gyri. The results of the present study on differences in activation further confirm existing theoretical hypotheses. Future studies should explore hemispheric differences in prefrontal brain function between IGD and non-IGD.

