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A bundled intervention improved human papillomavirus (HPV) vaccination rates by reducing missed vaccination opportunities during well-child visits. This approach shows promise for increasing HPV vaccine uptake in pediatric practices.

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Area of Science:

  • Public Health
  • Preventive Medicine
  • Vaccinology

Background:

  • Suboptimal human papillomavirus (HPV) vaccination rates and frequent missed vaccination opportunities are significant public health concerns.
  • Pediatric primary care settings represent a critical venue for addressing these gaps in HPV immunization coverage.

Purpose of the Study:

  • To evaluate the effectiveness of a bundled intervention designed to decrease missed HPV vaccination opportunities in pediatric practices.
  • To assess the impact of the intervention on initial and subsequent HPV vaccine doses during various types of patient visits.

Main Methods:

  • A pre-post design was employed across 24 primary care pediatric practices to evaluate the intervention's impact.
  • The bundled intervention comprised online clinician training, performance feedback on missed opportunities, and clinician prompts for HPV vaccination.
  • A secondary analysis compared intervention practices with contemporaneous comparison group practices.

Main Results:

  • Missed HPV vaccination opportunities for initial doses during well-child care (WCC) visits improved by 4.8 percentage points during the intervention period.
  • A modest improvement of 2.2 percentage points was observed for subsequent HPV vaccine doses during WCC visits.
  • Intervention practices showed improved initial HPV vaccination rates at WCC visits compared to comparison practices during the intervention period.

Conclusions:

  • The bundled intervention demonstrated effectiveness in improving HPV vaccination rates, particularly during well-child care visits.
  • The findings suggest that targeted interventions can successfully reduce missed vaccination opportunities and enhance adolescent immunization coverage.