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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
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Glue in Lockdown Technique to Embolize Peripheral Arterial Aneurysms
Shimpei Ikeda1, Takahiko Mine1, Shohei Mizushima1
1Department of Radiology, Nippon Medical School Chiba Hokusoh Hospital.
Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
|January 5, 2025
Summary
The novel "glue in lockdown technique" effectively controls blood flow for peripheral artery embolization using n-butyl cyanoacrylate (NBCA). This method successfully treated complex aneurysms unsuitable for conventional embolization.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Medical Device Technology
Background:
- Peripheral artery aneurysms and pseudoaneurysms pose treatment challenges, especially with abnormal blood flow or coagulopathy.
- Conventional embolization techniques may be insufficient for anatomically complex or hemodynamically challenging lesions.
Purpose of the Study:
- To introduce and evaluate the efficacy of the "glue in lockdown technique" for embolizing peripheral artery aneurysms/pseudoaneurysms.
- To assess the technical and clinical outcomes of this novel blood flow control method.
Main Methods:
- The "glue in lockdown technique" involves placing a vascular plug or coils proximally before n-butyl cyanoacrylate (NBCA) glue injection.
- Four challenging peripheral aneurysms (pulmonary artery pseudoaneurysms, pancreaticoduodenal arcade pseudoaneurysm, internal iliac artery aneurysm) were treated.
Main Results:
- The technique enabled reliable and rapid embolization, even in cases with coagulopathy.
- Successful treatment was achieved for hemodynamically and anatomically complicated peripheral aneurysms.
- The procedure demonstrated technical success and positive clinical outcomes.
Conclusions:
- The "glue in lockdown technique" is a safe and effective method for treating peripheral artery aneurysms and pseudoaneurysms.
- This approach offers a viable solution for complex cases where conventional embolization is not feasible.
- Further development and application of this technique for other vascular lesions are warranted.

