[The reference value of bone aging markers for the study of primary osteoporosis]

After the maturity period, human bones will experience aging changes such as decreased bone mass, abnormal trabecular structure and increased bone fragility. In recent years, with the development of aging research, research on bone aging markers has increased. Primary osteoporosis, which is related to aging, also belongs to the category of bone aging. This article will review the knowledge related to aging, bone aging markers and osteoporosis to explain the interrelationships between them, and combine some research progress to propose to learn from the bone aging markers research in the field of osteoporosis research. Combining bone aging markers and osteoporosis, the discussion around aging, bone aging, and osteoporosis will provide new ideas for further research on osteoporosis.