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The Printed Path to Healing: Advancing Wound Dressings through Additive Manufacturing.

Joana Galvão Duarte1,2, Ana Paula Piedade2, Bruno Sarmento3,4

  • 1Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto, 4050-313, Portugal.

Advanced Healthcare Materials
|January 6, 2025
PubMed
Summary

Additive manufacturing (AM) offers innovative solutions for advanced wound dressings, enabling customized, bioactive, and therapeutic options to improve healing outcomes. This technology addresses limitations of traditional wound care, paving the way for enhanced patient treatment.

Keywords:
additive manufacturingwound dressingwound healing

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Area of Science:

  • Biomaterials Engineering
  • Regenerative Medicine
  • Additive Manufacturing (3D Printing)

Background:

  • Traditional wound dressings face limitations in managing complex and diverse wound healing requirements.
  • There is an urgent need for innovative wound care alternatives beyond conventional treatments.
  • Additive manufacturing (AM) presents a transformative approach for developing advanced wound dressings.

Purpose of the Study:

  • To review the state-of-the-art in AM processes for wound dressing development.
  • To comprehensively examine AM applications in creating cellular-compatible, bioactive, and therapeutic agent-delivering dressings.
  • To analyze the potential of AM for patient-centric and responsive wound healing solutions.

Main Methods:

  • Comprehensive literature review focusing on AM techniques applied to wound dressings.
  • Analysis of studies covering various wound types, materials, and printing parameters.
  • Inclusion of data from in vitro, ex vivo, and in vivo investigations.

Main Results:

  • AM enables the production of highly functional and customizable wound dressings.
  • Review covers AM-fabricated dressings with enhanced cellular compatibility, bioactivity, and drug delivery capabilities.
  • Data synthesis includes materials, processes, printing parameters, and efficacy findings across different study types.

Conclusions:

  • Additive manufacturing holds significant promise for advancing wound healing.
  • AM facilitates the development of tailored, multi-functional dressings for diverse wound types.
  • Future prospects include translational and cost-effective enhancement of wound healing outcomes through AM.