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Biofeedback-Based Videogame May Improve Rage Attacks in Tourette Syndrome.

Jennifer Vermilion¹, Nicole Walsh¹, Matthew Tae¹

¹Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA.

Journal of Child and Adolescent Psychopharmacology

|January 6, 2025

Summary

This summary is machine-generated.

This study found that Mightier, a video game biofeedback therapy, is a feasible and acceptable treatment for reducing rage attacks in children with Tourette syndrome. Participants showed significant improvements in rage severity and aggression.

Keywords:

Tourette tic disorder biofeedback rage intermittent explosive disorder

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Area of Science:

Neurology and Psychiatry
Behavioral Therapy
Pediatric Medicine

Background:

Rage attacks (RA) affect 20%-40% of individuals with Tourette syndrome (TS), causing significant impairment.
Limited research exists on RA treatments in TS, with a focus on pharmacologic interventions.
Non-pharmacologic interventions may offer symptom improvement with fewer side effects.

Purpose of the Study:

To evaluate the feasibility and acceptability of Mightier, a video game-based biofeedback therapy, for treating rage attacks in youth with Tourette syndrome.
To assess the potential of Mightier in teaching emotional regulation through heart rate control.

Main Methods:

A 20-week single-arm trial enrolled 11 participants aged 6-12 with TS and RA.
Feasibility was assessed by enrollment rates, screen failures, retention, and device engagement.
Efficacy was measured using Clinical Global Impressions of Rage, ROARS, and MOAS pre- and post-intervention.

Main Results:

The study demonstrated feasibility with a 91% retention rate and consistent device engagement (38 min/week).
No adverse effects were reported during the intervention.
Significant improvements were observed in rage severity across all assessment measures, with all participants reporting improvement.

Conclusions:

Mightier is a feasible and acceptable intervention for children with Tourette syndrome and rage attacks.
The therapy demonstrated positive outcomes in reducing rage severity and aggression.
Mightier shows promise as a valuable tool for managing rage attacks in pediatric TS patients.