Reductive amination of triglycerides to fatty amines over a titanium oxide-supported Pt-Mo catalyst
Katsumasa Sakoda1, Harumi Furugaki1, Sho Yamaguchi1,2,3
1Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan. mizugaki.tomoo.es@osaka-u.ac.jp.
Abstract:
The reductive amination of naturally abundant triglycerides is a promising approach for the synthesis of fatty amines. However, existing catalytic systems for this transformation typically require harsh reaction conditions. Herein, we present a titanium oxide-supported platinum-molybdenum (Pt-Mo/TiO2) catalyst that promotes the reductive amination of triglycerides to fatty amines. The Pt-Mo/TiO2 catalyst exhibits a high activity under milder conditions, specifically at 1 MPa of H2, surpassing the performance of previously reported catalysts. A wide range of triglycerides, including cooking oils, are successfully converted into the corresponding fatty amines in high yields. The Pt-Mo/TiO2 catalyst is reusable and applicable to gram-scale reactions, demonstrating the high potential of Pt-Mo/TiO2 for green and sustainable fatty amine production.
Related Concept Videos
Preparation of Amines: Reductive Amination of Aldehydes and Ketones
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction
Preparation of Amines: Reduction of Amides and Nitriles
Amides can be reduced to primary, secondary, and tertiary amines using catalytic hydrogenation, active metals like Fe,...
Nitriles to Amines: LiAlH4 Reduction
As shown below, the mechanism involves three steps. Firstly, the hydride ion acting as a nucleophile attacks the nitrile carbon to form an anion. In the second step, a second equivalent of the hydride ion attacks the anion to...
Preparation of Amines: Reduction of Oximes and Nitro Compounds
Though catalytic hydrogenation can reduce nitrobenzenes, the reduction is nonselective in the presence of other functional groups. For instance, if nitrobenzene contains an aldehyde group,...
Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.


