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Postoperative changes in serum bromine value.

G C Gregoriadis, N S Apostolidis, A N Romanos

    Surgery, Gynecology & Obstetrics
    |March 1, 1985
    PubMed
    Summary

    Postoperative patients receiving bromine-rich anesthetics like halothane showed increased serum bromine. High bromine levels correlated with symptoms of acute brominism in some patients.

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    Area of Science:

    • Anesthesiology
    • Clinical Chemistry
    • Toxicology

    Background:

    • Anesthetics containing bromine are used in surgical procedures.
    • Elevated serum bromine levels can have clinical implications.

    Purpose of the Study:

    • To investigate changes in serum bromine levels after surgery.
    • To correlate postoperative bromine levels with clinical symptoms.

    Main Methods:

    • Serum bromine levels were measured in 40 postoperative patients.
    • Patients received anesthetics containing bromine (halothane, Fluothane).

    Main Results:

    • All patients receiving bromine-rich anesthetics exhibited increased postoperative serum bromine.
    • Eight of ten patients with elevated serum bromine showed significant symptoms.
    • Symptoms were consistent with acute brominism.

    Conclusions:

    • Bromine-rich anesthetics lead to elevated serum bromine postoperatively.
    • High postoperative serum bromine may cause acute brominism.
    • Monitoring bromine levels could be important in patients receiving these anesthetics.

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