Diagnosis and Management of Legg-Calvé-Perthes Disease in the Obese Pediatric Population

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Lauren Beckish1, Madison Ging1, Maria Mosman1

  • 1Department of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.

Journal of Orthopedics for Physician Assistants
|January 6, 2025
PubMed

Insights

Legg-Calvé-Perthes Disease (LCPD) in children is linked to poor blood flow in the hip. Obesity worsens LCPD, causing more severe symptoms and treatment challenges.

Area of Science:

  • Pediatric Orthopedics
  • Metabolic Bone Disease

Background:

  • Legg-Calvé-Perthes Disease (LCPD) involves disrupted blood flow to the pediatric femoral head, causing avascular necrosis.
  • The condition often affects children under 15, leading to bone weakening and deformity.

Purpose of the Study:

  • To investigate the significant impact of obesity on Legg-Calvé-Perthes Disease (LCPD) progression.
  • To understand how obesity influences LCPD diagnosis, severity, and treatment.

Main Methods:

  • Review of existing literature on LCPD and obesity.
  • Analysis of correlations between body mass index and LCPD outcomes.
  • Examination of hormonal and inflammatory factors in obese LCPD patients.

Main Results:

  • Obesity is associated with delayed LCPD diagnosis and increased disease severity.
  • Obese children with LCPD show a higher incidence of bilateral involvement.
  • Altered leptin, growth hormone, and inflammatory mediators are implicated in obese patients.

Conclusions:

  • Obesity presents unique challenges in managing pediatric LCPD.
  • Tailored treatment strategies are essential for obese children with LCPD for better outcomes.

Keywords:
Avascular NecrosisLegg-Calvé-Perthes DiseaseLegg-Calvé-Perthes disease progressionObesityOrthopedicsPediatrics

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