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Related Concept Videos

Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

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Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
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Related Experiment Video

Updated: May 7, 2025

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Amniotic Fluid Embolism After Cervical Ripening.

Madison French1, Teresa Bernardes2, Christine C Greves1

  • 1Obstetrics, Orlando Regional Medical Center, Orlando, USA.

Cureus
|January 6, 2025
PubMed
Summary
This summary is machine-generated.

Amniotic fluid embolism (AFE) is a rare, unpredictable obstetric emergency. This case highlights a potential association with labor induction and emphasizes the critical need for rapid diagnosis and supportive care for improved maternal and infant survival.

Keywords:
amniotic fluid embolism pathophysiologyamniotic fluid embolism treatmentcesarean birthfetal outcomepre-induction cervical ripening

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Area of Science:

  • Obstetrics and Gynecology
  • Critical Care Medicine
  • Perinatology

Background:

  • Amniotic fluid embolism (AFE) is a rare but devastating obstetric emergency with high maternal and infant mortality.
  • Diagnosis is often delayed, and treatment is primarily supportive, focusing on maternal stabilization and prompt infant delivery.
  • The role of cervical ripening and labor induction as risk factors for AFE remains controversial.

Observation:

  • A 31-year-old woman with gestational diabetes underwent cervical ripening and labor induction at 38 weeks gestation.
  • She developed sudden fetal bradycardia, followed by maternal hypoxia and hypotension after emergency cesarean delivery.
  • The patient was diagnosed with amniotic fluid embolism and disseminated intravascular coagulation.

Findings:

  • Despite the critical condition, prompt management including vasopressors and supportive care led to survival.
  • The infant, born with severe acidemia (umbilical cord pH 6.84), also survived without long-term sequelae.
  • This case suggests a possible link between labor induction methods and AFE, warranting further investigation.

Implications:

  • Early recognition and aggressive supportive care are crucial for improving outcomes in amniotic fluid embolism.
  • Exploring novel treatment protocols, such as the A-OK (atropine, ondansetron, ketorolac) protocol, may enhance patient management.
  • Further research is needed to clarify the potential association between labor induction and AFE risk.