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Updated: May 7, 2025

Real-Time, High-Throughput Microscopic Quantification of Human Neutrophil Extracellular Trap Release and Assessing the Pharmacology of Antagonists
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Real-Time, High-Throughput Microscopic Quantification of Human Neutrophil Extracellular Trap Release and Assessing the Pharmacology of Antagonists

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Neutrophil Extracellular Traps Drive Kidney Stone Formation

Zhiming Yang1,2, Xiong Chen1,2, Guannan Qi1,2

  • 1Department of Geriatric Urology, Xiangya International Medical Center, Xiangya Hospital, Central South University, Changsha, PR China.

Kidney Diseases (Basel, Switzerland)
|January 6, 2025
PubMed
Summary

Neutrophil extracellular traps (NETs) contribute to kidney stone formation and worsen kidney injury. Inhibiting NETs reduces calcium deposits and improves kidney function, identifying NETs as a biomarker for nephrolithiasis.

Keywords:
ApoptosisCalcium depositsKidney stonesNeutrophil extracellular trapsRenal tubular injury

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