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Novel Process for 3D Printing Decellularized Matrices
Published on: January 7, 2019
Research Progress in 3D Printed Biobased and Biodegradable Polyester/Ceramic Composite Materials: Applications and
Shunshun Zhu1,2, Hongnan Sun1, Taihua Mu1
1Laboratory of Food Chemistry and Nutrition Science, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences; Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, No. 2 Yuan Ming Yuan West Road, Haidian District, P.O. Box 5109, Beijing 100193, China.
Biobased polyester composites offer promising alternatives for bone implants, enhancing bone defect repair through bone tissue engineering (BTE) scaffolds. 3D printing advances scaffold precision for improved clinical applications.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Materials Engineering
Background:
- Bone defects require effective treatments like bone implant transplantation.
- Biobased and biodegradable polyester composites offer favorable mechanical and degradation properties for bone implants.
- Bone tissue engineering (BTE) utilizes scaffolds to mimic the bone microenvironment, accelerating repair.
Purpose of the Study:
- To review the physical properties of BTE scaffolds.
- To summarize recent strategies for improving biobased and biodegradable polyester/ceramic composite scaffolds.
- To discuss future prospects and clinical production challenges in the field.
Main Methods:
- Literature review of recent advancements in BTE scaffolds.
- Analysis of strategies for enhancing polyester/ceramic composite properties.
- Examination of 3D printing's role in scaffold fabrication.
Main Results:
- Biobased polyester composites show potential as bone implant materials.
- Composite scaffolds enhance bone formation and accelerate repair.
- 3D printing technology allows for precise, reproducible, and flexible scaffold preparation.
Conclusions:
- Biobased and biodegradable polyester/ceramic composites are promising for BTE scaffolds.
- Advancements in scaffold design and 3D printing are crucial for clinical translation.
- Further research is needed to address challenges in large-scale clinical production.

