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Updated: Jun 3, 2025

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Resilience mechanisms underlying Alzheimer's disease

Chu Shi Chew1, Jia Yee Lee1, Khuen Yen Ng2

  • 1School of Health Science, IMU University, 57000, Kuala Lumpur, Malaysia.

Metabolic Brain Disease
|January 6, 2025
PubMed
Summary

Individuals with Alzheimer's disease (AD) neuropathology but no cognitive decline show resilience. Understanding these protective factors, like APOE2 and BDNF, offers new therapeutic avenues for AD.

Keywords:
AD neuropathologyAlzheimer’s diseaseMolecular pathwaysResilience mechanisms

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