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Updated: May 7, 2025

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
MRI grading using the neuropathy score-reporting and data system with electrodiagnostic correlation in radial
Benjamin Abiri1, David Kopylov1, Mohammad Samim1
1Department of Radiology, NYU Langone Orthopedic Hospital, 301 East 17Th Street, 6Th Floor, Radiology , New York, NY, 10003, USA.
Objective:
To evaluate the Neuropathy Score-Reporting and Data System (NS-RADS) MRI grading system in conjunction with electrodiagnostic (EDx) testing for radial neuropathy at the elbow.
Materials And Methods:
Patients presenting between 2010 and 2023 with suspected radial neuropathy who underwent both EDx testing in the form of electromyography and nerve conduction studies and MRI within a 12-month period were evaluated. Three blinded radiologists used the NS-RADS grading system to evaluate nerve entrapment (E grades), muscle denervation (M grades) proximally within the supinator/extensor carpi radialis brevis (ECRB), and more distally within the forearm extensor muscles. These grades and the presence of lateral epicondylitis were then correlated with EDx abnormalities.
Results:
Forty-nine participants were included. Inter-reader reliability for M grades in the forearm extensor muscles was good (ICC = 0.90 [95% CI = 0.83 - 0.94], p < 0.001), as was reliability for the supinator/ECRB muscles (ICC = 0.91 [95% CI = 0.86-0.95], p < 0.001). Inter-reader reliability for E grades was moderate (ICC = 0.83 [95% CI = 0.69-0.90], p < 0.001). Patients with positive EDx studies had a significantly different distribution of M grades for the forearm extensors and supinator/ECRB than those with negative studies (all p values < 0.001). However, overall consensus reads showed no significant difference in the distribution of E grades between patients with positive and negative EDx studies.
Conclusion:
Muscle grading strongly correlated with EDx positivity, with a high level of inter-reader agreement for muscle denervation-related alterations. Nerve grading, however, did not show a statistical correlation.
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