Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

  1. Home
  3. Role Of Indocyanine Green Fluorescence Imaging In Margin Assessment And Recurrence-free Survival In Laparoscopic Parenchyma-sparing Hepatectomy For Neuroendocrine Tumor Liver Metastases.
  1. Home
  3. Role Of Indocyanine Green Fluorescence Imaging In Margin Assessment And Recurrence-free Survival In Laparoscopic Parenchyma-sparing Hepatectomy For Neuroendocrine Tumor Liver Metastases.

Related Experiment Video

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

177

Role of indocyanine green fluorescence imaging in margin assessment and recurrence-free survival in laparoscopic

Gaoming Wang1, Chenghao Liu1, Weijun Qi1

  • 1Department of General Surgery, Peking University Third Hospital, Beijing, 100191, China.

Surgical Endoscopy
|January 6, 2025

View abstract on PubMed

Summary
This summary is machine-generated.
Keywords:
Indocyanine green fluorescence imagingIntrahepatic recurrenceLaparoscopic parenchyma-sparing hepatectomyNeuroendocrine tumor liver metastasesRecurrence-free survivalSurgical margins

More Related Videos

Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
03:23

Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining

Published on: March 17, 2023

686
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
03:27

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

Published on: January 31, 2025

332

Related Experiment Videos

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

177
Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
03:23

Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining

Published on: March 17, 2023

686
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
03:27

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

Published on: January 31, 2025

332

Indocyanine green (ICG) fluorescence imaging in laparoscopic liver surgery for neuroendocrine tumors improved surgical margins. While recurrence-free survival showed a trend toward improvement, larger studies are needed to confirm benefits for neuroendocrine liver metastases (NELM) patients.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Medical Imaging

Background:

  • Neuroendocrine liver metastases (NELM) present significant management challenges due to low resectability and high recurrence rates.
  • Laparoscopic parenchyma-sparing hepatectomy (LPSH) is a key surgical approach for NELM.
  • Indocyanine green (ICG) fluorescence imaging offers potential for enhanced tumor visualization and margin assessment during surgery.

Purpose of the Study:

  • To evaluate the impact of ICG fluorescence imaging on perioperative outcomes.
  • To assess the effect of ICG fluorescence on recurrence-free survival (RFS) in NELM patients undergoing LPSH.
  • To determine the utility of ICG in improving surgical precision for NELM.

Main Methods:

  • A retrospective cohort study included 51 patients with NELM undergoing LPSH.
  • Data collected included sociodemographics, laboratory parameters, surgical results, and follow-up outcomes.
  • Patients were divided into ICG fluorescence imaging and non-ICG groups.

    • Main Results:

    • No significant baseline differences were found between the ICG and non-ICG groups.
    • Pathologically positive surgical margins were significantly lower in the ICG group (1.3% vs. 16.4%, p < 0.001).
    • Median recurrence-free survival (RFS) was longer in the ICG group (38.0 vs. 29.0 months, p = 0.086), though not statistically significant.

    Conclusions:

    • ICG fluorescence imaging in LPSH for NELM may lead to improved surgical margins.
    • A trend towards enhanced RFS was observed with ICG use, suggesting potential long-term benefits.
    • Larger prospective studies are warranted to validate the impact of ICG on long-term prognosis in NELM management.