Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Macrophages in Pacinian corpuscles.

C Ide, K Tohyama

    Acta Anatomica
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Macrophages reside in Pacinian corpuscles, acting as scavengers. These specialized cells maintain the corpuscle

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Personalized Food Avoidance Dietary Approach for Psoriasis and Hypertension: A Case Study and Pilot Trial.

    Nigerian journal of clinical practice·2026
    Same author

    mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.

    Science advances·2020
    Same author

    Present status and perspective of laboratory hematology in Japan: On the standardization of blood cell morphology including myelodysplasia: On behalf of the Japanese Society for Laboratory Hematology.

    International journal of laboratory hematology·2018
    Same author

    Broader head, stronger bite: In vivo bite forces in European eel Anguilla anguilla.

    Journal of fish biology·2017
    Same author

    Locomotor improvement of spinal cord-injured rats through treadmill training by forced plantar placement of hind paws.

    Spinal cord·2015
    Same author

    Head shape dimorphism in European glass eels (Anguilla anguilla).

    Zoology (Jena, Germany)·2015

    Area of Science:

    • Neuroscience
    • Cell Biology
    • Histology

    Background:

    • Pacinian corpuscles are mechanoreceptors crucial for touch sensation.
    • The cellular composition of the outer bulb region of Pacinian corpuscles is not fully understood.
    • The role of specific cell types within Pacinian corpuscles requires further investigation.

    Purpose of the Study:

    • To identify and characterize macrophages within the outer bulb of Pacinian corpuscles across different species.
    • To investigate the functional activity of these macrophages using horseradish peroxidase (HRP) uptake.

    Main Methods:

    • Light and electron microscopy were employed to visualize cellular structures.
    • Macrophages were identified based on morphology and location within the Pacinian corpuscle outer bulb.

    Related Experiment Videos

  • Horseradish peroxidase (HRP) was used as a tracer to assess cellular uptake and phagocytic activity.

    • Main Results:

    • Macrophages were consistently observed in the outer bulb region of Pacinian corpuscles in mice, monkeys, and humans.
    • These macrophages exhibited characteristic features including vesicles, vacuoles, and cytoplasmic processes.
    • Injected HRP was readily taken up by macrophages in the outer bulb, indicating active phagocytosis.

    Conclusions:

    • Macrophages are integral components of the Pacinian corpuscle's outer bulb in multiple mammalian species.
    • These macrophages likely function as scavengers, maintaining the internal homeostasis of the corpuscle.
    • The findings contribute to a deeper understanding of Pacinian corpuscle structure and function.