A preliminary clinical study related to vestibular migraine and cognitive dysfunction

Area of Science:

• Neurology
• Neuroscience
• Ophthalmology

Background:

• Vestibular migraine (VM) is a common disorder causing recurrent vertigo and often accompanied by cognitive dysfunction.
• Patients with VM frequently report memory loss and other cognitive issues, causing significant distress.

Purpose of the Study:

• To explore the characteristics and risk factors of cognitive dysfunction in VM patients.
• To analyze the relationship between cognitive function, vestibular function, and psychological factors in VM.

Main Methods:

• 61 VM patients and 30 healthy controls underwent cognitive (ACE-R) and vestibular function tests.
• VM patients were categorized based on cognitive dysfunction (VM-CogD) and dizziness severity.
• Correlation and ROC analyses identified factors influencing cognitive impairment.

Main Results:

• VM patients exhibited lower scores in memory, verbal fluency, language, and visuospatial function compared to controls.
• Vestibular dysfunction (semicircular canals, VOR, VSR) was significantly higher in VM patients.
• Canal paresis, age, education, and disease duration were significant predictors of cognitive dysfunction in VM.

Conclusions:

• VM patients present with diverse vestibular and cognitive impairments.
• Cognitive function in VM is influenced by vestibular function, age, education, and disease duration.
• Functional disturbances, anxiety, and depression may contribute to cognitive dysfunction in VM.