Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
The Roles of Bacteria and Fungi in Plant Nutrition02:11

The Roles of Bacteria and Fungi in Plant Nutrition

34.7K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
34.7K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

1.3K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.3K
Surface Membrane Barriers01:18

Surface Membrane Barriers

653
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
653
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

5.6K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Analysis of clinical characteristics of renal oncocytoma: 26 cases report].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2012
Same author

[Expression of Na+/H+ antiporter gene KsNHX1 in Kochia sieversiana under saline-alkali stress].

Ying yong sheng tai xue bao = The journal of applied ecology·2012
Same author

Fasudil, a Rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice.

International journal of molecular sciences·2012
Same author

[Analysis of genes and genetic susceptibility of olfactory disorders].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2012
Same author

Top-down processing of symbolic meanings modulates the visual word form area.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2012
Same author

Oxidative stress acts on special membrane proteins to reduce the viability of Pseudomonas syringae pv tomato.

Journal of proteome research·2012

Related Experiment Video

Updated: May 7, 2025

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
09:38

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

1.9K

Vitiligo: are microbes to blame?

Xiaoyu Liu1, Jia Liu1

  • 1Department of Pharmacy, Xiangyang key Laboratory of Special Preparation of Vitiligo, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China.

Bioscience of Microbiota, Food and Health
|January 7, 2025
PubMed
Summary

Microbes like bacteria and viruses may play a role in vitiligo, a skin depigmentation disease. Understanding these microbial connections could lead to new vitiligo treatments.

Keywords:
autoimmune diseasemicrobesvitiligo

More Related Videos

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

12.6K
Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
11:00

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress

Published on: August 31, 2015

8.1K

Related Experiment Videos

Last Updated: May 7, 2025

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
09:38

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

1.9K
Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

12.6K
Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
11:00

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress

Published on: August 31, 2015

8.1K

Area of Science:

  • Dermatology
  • Immunology
  • Microbiology

Background:

  • Vitiligo is a common acquired skin depigmentation disorder characterized by melanocyte loss.
  • The exact causes and mechanisms of vitiligo remain unclear, posing treatment challenges.
  • Vitiligo is recognized as an autoimmune condition, with microbes known to modulate immune responses.

Purpose of the Study:

  • To review the association between microbes and vitiligo.
  • To explore potential mechanisms linking microbial involvement to vitiligo development.
  • To provide insights into future therapeutic strategies for vitiligo.

Main Methods:

  • Literature review of studies investigating microbial involvement in vitiligo.
  • Analysis of proposed mechanisms of microbial influence on vitiligo pathogenesis.
  • Synthesis of current understanding on the microbe-vitiligo correlation.

Main Results:

  • Evidence suggests a correlation between specific microorganisms (bacteria, viruses) and vitiligo.
  • Microbes may influence vitiligo through immune system modulation and other pathways.
  • The review consolidates existing knowledge on microbial factors in vitiligo.

Conclusions:

  • Microbial factors are increasingly implicated in the pathogenesis of vitiligo.
  • Further research into these microbial connections may reveal novel therapeutic targets.
  • Understanding the microbe-vitiligo axis is crucial for advancing treatment options.