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Paediatric-to-adult transition in type 1 diabetes: A two-centre experience of a structured program, 2014 to 2022
Gaëlle Vermillac1,2, Charlotte Lafont3,4, Cécile Godot1
1Endocrinologie, Diabétologie Et Gynécologie Pédiatrique, Hopital Necker-Enfants Malades, Université Paris Cité, AP-HP centre, Paris, France.
Insights
A coordinated transition process helps most Type 1 diabetes patients attend adult care. Younger age at diagnosis and poorer glycemic control predict non-adherence to adult follow-up for T1D care.
Area of Science:
- Endocrinology
- Paediatric Healthcare
- Transition Medicine
Background:
- Transitioning from pediatric to adult healthcare is critical for Type 1 diabetes (T1D) patients.
- A structured, coordinated process may improve adherence to adult care follow-up.
Purpose of the Study:
- To outline a joint pediatric and adult diabetology transition process.
- To compare follow-up adherence in patients undergoing this transition.
Main Methods:
- Retrospective study involving patients from 2014-2021 in pediatric diabetology.
- Analysis of patient progression to adult care follow-up.
Main Results:
- 137/183 patients transitioned to adult care, with improved HbA1c (7.8%) and stable complication rates.
- 25.1% of patients did not attend adult care; younger diagnosis age and higher pre-transition HbA1c predicted non-adherence.
- Most patients (88.5%) felt well-prepared for the transition.
Conclusions:
- A gradual, coordinated transition process facilitates adult care follow-up for most T1D patients.
- Early diagnosis age and suboptimal glycemic control are linked to poor adherence to adult care.
- The transition process positively impacted patient preparedness and diabetes management perception.
Background:
Transition from paediatric to adult healthcare is a turning point for patients with Type 1 diabetes (T1D). A gradual coordinated process connecting paediatric and adult healthcare providers may improve adherence to adult follow-up.
Aims:
To describe a transition process developed jointly by paediatric and adult diabetology units and compare patients progressing or not to follow-up in adult care setting.
Materiel And Methods:
Retrospective study in one paediatric and one adult diabetology department. Patients following from 2014 to 2021 in the paediatric department were eligible.
Results:
At transition, the 183 patients included had a median age of 19 [18.5-19.5] years, T1D duration of 10.5 [7.0-14.0] years, and HbA1c of 8.4% [7.5-9.2%]; 30.6% were treated by continuous subcutaneous insulin infusion. Two years after exiting paediatric care, the subgroup transitioning to adult care at the planned site (n = 137) had a median HbA1c of 7.8% [7.0-8.7]; 13.1% had retinopathy (non-significant change), and 10.8% had changed their insulin treatment. Of the remaining 46/183 (25.1%) patients, 33/46 (71.7%) had no adult care visits at any site reported. Independent predictors of non-adherence to adult follow-up were younger age at TID diagnosis (adjusted odds ratio, 0.91 [0.83-0.99]) and higher pre-transition HbA1c (+1.39 [1.11-1.80]). Among the 52 (28.4%) patients who completed a questionnaire on perceptions, 88.5% reported being well prepared and 90.5% a neutral or positive impact on their diabetes.
Conclusion:
With a gradual coordinated transition process, most T1D patients attended adult care follow-up visits. Younger age at diagnosis and worse glycaemic control were associated with lack of adherence to planned adult care follow-up.
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