Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A hypothalamic circuit that modulates feeding and parenting behaviours.

Nature·2025

Same author

A Hypothalamic Circuit that Modulates Feeding and Parenting Behaviors.

bioRxiv : the preprint server for biology·2024

Same author

Preoptic bombesin-like receptor-3 neurons heat it up.

Temperature (Austin, Tex.)·2022

Same author

A distinct hypothalamus-to-β cell circuit modulates insulin secretion.

Cell metabolism·2022

Same author

Cre Recombinase Driver Mice Reveal Lineage-Dependent and -Independent Expression of Brs3 in the Mouse Brain.

eNeuro·2021

Same author

Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways.

Cell metabolism·2021

Same journal

Pitch selectivity in ferret auditory cortex.

Current biology : CB·2026

Same journal

A cell size-dependent competition between geometry and polarity governs nuclear and spindle positioning in early embryos.

Current biology : CB·2026

Same journal

Trophic cascades drive sustainability in the agricultural heritage rice-fish coculture system.

Current biology : CB·2026

Same journal

Tracking Satb2-positive retinal ganglion cells in zebrafish unveils developmental functional reorganization.

Current biology : CB·2026

Same journal

RhoGAP54D promotes cell size asymmetry and inhibits pulsatile myosin activity in Drosophila neural stem cells.

Current biology : CB·2026

Same journal

Increased rates of hybridization in swordtails are associated with water pollution.

Current biology : CB·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 7, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Thermoregulation: When cooling cools and heating heats.

Ramón A Piñol¹

¹Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Current Biology : CB

|January 7, 2025

Summary

This summary is machine-generated.

Researchers discovered a novel neural circuit enabling thermoregulatory inversion in endotherms. This finding challenges traditional understanding of body temperature control mechanisms.

More Related Videos

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

Related Experiment Videos

Last Updated: May 7, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

Area of Science:

Neuroscience
Physiology
Thermoregulation

Background:

Endotherms maintain stable body temperatures despite external fluctuations.
Traditional thermoregulation involves warming in cold and cooling in heat.

Purpose of the Study:

To identify neural mechanisms underlying thermoregulatory inversion.
To investigate the brain's capacity for paradoxical temperature control.

Main Methods:

Utilized advanced neuroimaging techniques.
Employed physiological monitoring during temperature challenges.

Main Results:

Identified a specific neural circuit responsible for thermoregulatory inversion.
Demonstrated the capacity for reversed body temperature responses.

Conclusions:

Thermoregulatory inversion is a newly identified physiological phenomenon.
This discovery expands our understanding of neural control of body temperature.