Related Experiment Video

Updated: Aug 7, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Growth patterns in children hospitalized because of caloric-deprivation failure to thrive

N S Ellerstein, B E Ostrov

    American Journal of Diseases of Children (1960)
    |February 1, 1985
    PubMed

    Insights

    Infants with suspected caloric-deprivation failure to thrive (CDFTT) typically gain weight within two weeks. Younger infants (<6 months) show rapid weight gain in 2-3 days, indicating effective nutritional intervention.

    Area of Science:

    • Pediatrics
    • Nutrition Science
    • Growth Monitoring

    Background:

    • Caloric-deprivation failure to thrive (CDFTT) often necessitates hospitalization for diagnosis.
    • Accelerated weight gain in a hospital setting is the primary diagnostic criterion for CDFTT.

    Purpose of the Study:

    • To determine the timeframe for weight gain initiation in infants and children with CDFTT.
    • To assess if the speed of weight gain in CDFTT patients is age-dependent.

    Main Methods:

    • Retrospective analysis of 57 pediatric patients diagnosed with CDFTT.
    • Development and application of a "growth quotient" to quantify growth rate.
    • Evaluation of weight gain timelines relative to age.

    Main Results:

    • Nearly all 57 children with CDFTT initiated weight gain within two weeks.
    • Infants under 6 months with CDFTT typically started gaining weight within 2-3 days.
    • Older infants and children with CDFTT exhibited initial corrective growth rates comparable to or exceeding those of younger infants.

    Conclusions:

    • Rapid weight gain is a consistent early indicator for CDFTT diagnosis in hospitalized infants and children.
    • Age does not significantly impede the initiation of weight gain in response to nutritional support for CDFTT.
    • The "growth quotient" provides a valuable metric for assessing growth recovery in pediatric malnutrition.

    More Related Videos

    A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect05:04

    A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

    Published on: September 22, 2023

    Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System06:19

    Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System

    Published on: April 19, 2024

    Related Concept Videos

    Nature and Nurture01:10

    Nature and Nurture

    Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
    Overview of Protein Metabolism01:21

    Overview of Protein Metabolism

    Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
    Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
    Metabolic States of the Body: Fasting and Starvation01:24

    Metabolic States of the Body: Fasting and Starvation

    During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
    Inborn Errors of Metabolism01:20

    Inborn Errors of Metabolism

    Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
    Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

    Parentral Nutrition: Centeral and Peripheral Parental Nutrition

    Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
    PN can be administered through two primary routes:
    1. Central Parenteral Nutrition (CPN):
    CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
    Oxygen Requirements and Growth Patterns01:29

    Oxygen Requirements and Growth Patterns

    Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...