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Updated: Jun 3, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
Published on: December 29, 2021
Properties of Maxentropic DNA Synthesis Codes
Kees Schouhamer Immink1, Jos H Weber2, Kui Cai3
1Turing Machines Inc., Willemskade 15, 3016 DK Rotterdam, The Netherlands.
Abstract:
Low-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword length. We compare the performance of low-complexity nibble replacement (NR) codes, which are designed to minimize the synthesis time, with the performance of maxentropic low-weight codes. Finally, the asymptotic redundancy and information rate of codes with a runlength limitation are investigated.
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