Modeling and Visual Simulation of Bifurcation Aneurysms Using Smoothed Particle Hydrodynamics and Murray's Law

Aneurysm modeling and simulation play an important role in many specialist areas in the field of medicine such as surgical education and training, clinical diagnosis and prediction, and treatment planning. Despite the considerable effort invested in developing computational fluid dynamics so far, visual simulation of blood flow dynamics in aneurysms, especially the under-explored aspect of bifurcation aneurysms, remains a challenging issue. To alleviate the situation, this study introduces a novel Smoothed Particle Hydrodynamics (SPH)-based method to model and visually simulate blood flow, bifurcation progression, and fluid-structure interaction. Firstly, this research consider blood in a vessel as a kind of incompressible fluid and model its flow dynamics using SPH; and secondly, to simulate bifurcation aneurysms at different progression stages including formation, growth, and rupture, this research models fluid particles by using aneurysm growth mechanism simulation in combination with vascular geometry simulation. The geometry incorporates an adjustable bifurcation structure based on Murray's Law, and considers the interaction between blood flow, tissue fluid, and arterial wall resistance. Finally, this research discretizes the computation of wall shear stress using SPH and visualizes it in a novel particle-based representation. To examine the feasibility and validity of the proposed method, this research designed a series of numerical experiments and validation scenarios under varying test conditions and parameters. The experimental results based on numerical simulations demonstrate the effectiveness and efficiency of proposed method in modeling and simulating bifurcation aneurysm formation and growth. In addition, the results also indicate the feasibility of the proposed wall shear stress simulation and visualization scheme, which enriches the means of blood analysis.