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Effect of White Tea on Leptin and Asprosin Levels in Rats Feeding a High-Fat Diet
Adnan Yilmaz1, Merve Nur Toraman1, Sibel Mataraci Karakas1
1Department of Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Türkiye.
Life (Basel, Switzerland)
|January 8, 2025
Summary
White tea consumption significantly reduced body weight, leptin, and asprosin levels in rats on a high-fat diet. This suggests white tea
Area of Science:
- Nutritional Science
- Biochemistry
- Pharmacology
Background:
- Obesity affects over 600 million people globally, contributing to serious health issues like diabetes and metabolic syndrome.
- White tea possesses potent antioxidant properties, making it a potential natural intervention for metabolic disorders.
Purpose of the Study:
- To investigate the effects of white tea on body weight, leptin, and asprosin levels in a rat model of obesity.
- To evaluate the preventative and therapeutic potential of white tea against high-fat diet-induced metabolic disturbances.
Main Methods:
- 72 male Sprague-Dawley rats were divided into 9 groups, receiving either white tea or orlistat with a high-fat diet.
- Serum levels of leptin, asprosin, and insulin were quantified using ELISA.
- Oxidative stress indicators were also assessed.
Main Results:
- White tea administration significantly decreased body weight in rats fed a high-fat diet.
- Serum levels of leptin and asprosin were notably reduced following white tea treatment.
- White tea also mitigated oxidative stress markers.
Conclusions:
- White tea demonstrates efficacy in reducing body weight and improving metabolic markers associated with obesity.
- Its antioxidant properties and minimal side effects make it a promising natural agent for managing obesity-related health conditions.
