Related Experiment Video

Updated: Jun 3, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

465

International Nephrology Masterclass in Chronic Kidney Disease: Rationale, Summary, and Future Perspectives

Francesco Pesce1,2, Maria Vadalà2, Edgar Almeida3

  • 1Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Life (Basel, Switzerland)
|January 8, 2025
PubMed

Insights

Chronic kidney disease (CKD) affects over 844 million globally, yet awareness is low. An international masterclass aimed to improve CKD diagnosis and treatment by sharing expert insights and real-world data.

Area of Science:

  • Nephrology
  • Public Health

Background:

  • Chronic kidney disease (CKD) affects over 10% of the global population, surpassing the prevalence of diabetes, cancer, and HIV.
  • Despite its high prevalence, CKD remains underrecognized compared to other major diseases.
  • A projected decline in the nephrology workforce and interest in the field necessitates innovative educational strategies.

Purpose of the Study:

  • To establish an international educational platform for nephrology professionals.
  • To disseminate the latest research and best practices in CKD diagnosis and management.
  • To foster the global implementation of evidence-based CKD care through real-world case examples.

Main Methods:

  • An international masterclass was conducted from November 2022 to March 2023 in Milan, Italy.
  • The program featured leading experts sharing unbiased education on CKD and its comorbidities.
  • Discussions focused on recent research data and practical application in 'real-life' patient outcomes.

Main Results:

  • The masterclass provided a comprehensive overview of current CKD knowledge and future directions.
  • Key lectures and discussions facilitated the exchange of cutting-edge information among international participants.
  • The program aimed to create a multiplier effect, promoting the adoption of best practices worldwide.

Conclusions:

  • The International Nephrology Masterclass (INM) successfully created a platform for advanced nephrology education.
  • Sharing real-world patient outcomes and recent research is crucial for improving CKD care globally.
  • Future developments will focus on sustaining this educational momentum and expanding its reach.

Keywords:
CKDdiabetesdiseaseeducationalgendergeneticshypertensionkidneymasterclassnephrology

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.2K
Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney08:53

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

44.4K

Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
32.9K
Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
62
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
261
Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
53
Nephrons01:10

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.1K
Renal Drug Clearance: Overview01:06

Renal Drug Clearance: Overview

Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
114