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Updated: Jun 18, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Project Initiate: A Clinical Feasibility Trial of Equitable Access to Early Neurodevelopmental Therapy
Jessica Trenkle1, Alison Liddle2, Lynn Boswell1
1Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Insights
Home physical therapy (PT) is feasible for infants with public insurance after NICU/CICU discharge. Early PT improved motor outcomes, highlighting the need to address early intervention (EI) access barriers for these vulnerable infants.
Area of Science:
- Pediatrics
- Neonatal Care
- Physical Therapy
Background:
- Early intervention (EI) programs are crucial for infant development, yet many eligible infants face service initiation delays or are excluded.
- Disparities exist in EI enrollment, with infants holding public insurance showing lower participation rates.
- Neonatal or cardiac intensive care unit (NICU/CICU) graduates, particularly those with public insurance, may benefit from timely post-discharge support.
Purpose of the Study:
- To assess the feasibility of promptly initiating home-based physical therapy (PT) for infants with public insurance after NICU/CICU discharge.
- To compare early motor outcomes between infants receiving home PT and those receiving standard care.
- To identify barriers affecting early intervention (EI) access for this population.
Main Methods:
- A pilot study involving infants discharged from a NICU/CICU with public insurance and eligible for Illinois EI services.
- The intervention group (n=46) received weekly home-based PT until 3-4 months corrected age (CA); the control group (n=14) received standard care.
- Infants underwent the Test of Infant Motor Performance (TIMP) at discharge and 3-4 months CA; PT and EI initiation rates were tracked.
Main Results:
- 78% of the intervention group received at least one PT session by 3-4 months CA, demonstrating feasibility.
- Only 13% of the entire cohort received any EI therapy, indicating a significant access gap.
- Infants receiving 8-10 PT sessions showed a greater improvement in TIMP Z-scores (>0.5 SD).
Conclusions:
- Prompt home-based PT is a feasible approach for urban infants with public insurance, potentially optimizing neuroplastic changes.
- The study highlights significant barriers to early intervention (EI) access for infants with public insurance.
- Addressing identified barriers is crucial to improve EI service delivery for at-risk infants.
Abstract:
Background/Objectives: Despite evidence of the effectiveness of early intervention (EI) programs, eligible infants often experience delays in initiation of services or fail to receive services entirely. Disparities have been documented, including lower enrollment rates for infants with public insurance. The objective of this pilot study was to evaluate the feasibility of initiating home physical therapy (PT) services promptly after neonatal or cardiac intensive care unit (NICU/CICU) discharge for infants with public insurance and to assess early motor outcomes for children who received study therapy compared with a standard of care group. Methods: Infants were recruited if discharged from a study NICU/CICU, had public insurance, and were eligible for Illinois EI services. Infants living in Chicago (n = 46) received weekly home-based PT from a study therapist until 3-4 months corrected age (CA). Infants living outside Chicago received standard of care services and served as a control group (n = 14). At discharge, infants were referred to EI and underwent the Test of Infant Motor Performance (TIMP). Outcomes at 3-4 months CA included initiation rates for study PT and EI and follow-up TIMP testing. Results: By 3-4 months CA, 78% of the intervention group had received ≥1 PT session. In contrast, just 13% of the entire cohort had received any EI therapy. Infants who had 8-10 PT sessions in the first 3-4 months after discharge were more likely to have a change in the TIMP Z-score of >0.5 SD. Conclusions: Prompt transition to home therapy was feasible for infants with public insurance in an urban setting who may benefit most due to the potential for neuroplastic change. Addressing barriers identified in this study may assist in improving access to EI for young infants.
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