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Updated: Jun 3, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Recent Advances in the Synthesis of Cyclic Sulfone Compounds with Potential Biological Activity
Hong-Li Huang1, Ya-Qian Shi1, Jia-Xin Ning1
1College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.
Abstract:
In recent years, cyclic sulfone compounds, a subset of biologically active heterocyclic compounds, have gained considerable attention due to their potential in the development of novel active pharmaceutical ingredients. This review focuses on identifying simple, mild, environmentally friendly, and efficient synthesis methods. Various catalytic approaches for the synthesis of cyclic sulfone compounds are systematically reviewed, highlighting their advantages and potential applications in pharmaceutical development.
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