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Functionalities of Tremella fuciformis Polysaccharides Modified with Gallic Acid
Tai-Ti Liu1, Kai-Siang Hong1, Tsung-Shi Yang2
1Department of Food Science, Yuanpei University of Medical Technology, No. 306 Yuanpei Street, Hsinchu 30015, Taiwan.
Molecules (Basel, Switzerland)
|January 8, 2025
Summary
Modified Tremella fuciformis polysaccharides (TFPs) with gallic acid (GA) and zinc ions showed enhanced antioxidant and antimicrobial activities. The TFP-GA-Zn complex notably improved effectiveness against S. aureus and E. coli.
Area of Science:
- Biochemistry
- Food Science
- Materials Science
Background:
- Edible mushrooms like Tremella fuciformis are rich in polysaccharides (TFPs) with potential bioactivities.
- Gallic acid (GA) is a known antioxidant and antimicrobial compound.
- Metal ion complexation can enhance the properties of polysaccharides.
Purpose of the Study:
- To chemically modify TFPs with GA.
- To form complexes of modified TFPs with zinc ions (TFP-GA-Zn).
- To investigate the antioxidant and antimicrobial properties of the modified TFPs and their complexes.
Main Methods:
- Extraction and modification of Tremella fuciformis polysaccharides with gallic acid.
- Complexation of TFP-GA with zinc ions.
- Evaluation of antioxidant activities using DPPH, nitric oxide, and hydrogen peroxide scavenging assays, and reducing/chelating assays.
- Assessment of antimicrobial activity against Staphylococcus aureus and Escherichia coli.
Main Results:
- TFP-GA exhibited significant antioxidant activity, including DPPH, nitric oxide, and hydrogen peroxide scavenging.
- TFP-GA showed enhanced reducing and iron-chelating abilities compared to unmodified TFP.
- The TFP-GA-Zn complex demonstrated superior antimicrobial efficacy against S. aureus and E. coli compared to TFP-GA.
Conclusions:
- Gallic acid modification and zinc complexation effectively enhance the antioxidant and antimicrobial functionalities of Tremella fuciformis polysaccharides.
- The TFP-GA-Zn complex represents a promising functional ingredient with potential applications in food and pharmaceutical industries.
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