Related Experiment Video
Updated: Aug 9, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 18, 2011
Acute epiglottitis in children
Insights
Acute epiglottitis in children can lead to serious complications and death. Prompt airway management via direct laryngoscopy and nasotracheal intubation is crucial, alongside appropriate antibiotic treatment.
Area of Science:
- Pediatric Medicine
- Otolaryngology
- Infectious Diseases
Background:
- Acute epiglottitis is a life-threatening condition in children.
- Management strategies and outcomes have evolved over time.
- Understanding complications is vital for effective treatment.
Purpose of the Study:
- To review the management and outcomes of acute epiglottitis in children.
- To identify common complications and associated mortality.
- To recommend optimal airway management and antibiotic protocols.
Main Methods:
- Retrospective review of 161 pediatric patients with acute epiglottitis.
- Analysis of complications, mortality rates, and treatment interventions.
- Evaluation of airway management techniques and antibiotic sensitivities.
Main Results:
- Five deaths occurred among 34 patients with 45 complications.
- Direct laryngoscopy and nasotracheal intubation under general anesthesia with skilled assistance is the preferred airway management.
- Antibiotic resistance to ampicillin was noted in 20% of cases.
Conclusions:
- Skilled airway management is critical to prevent respiratory arrest.
- Early administration of chloramphenicol (with or without ampicillin) after blood cultures is recommended.
- This study highlights the importance of established protocols for managing acute epiglottitis.
Abstract:
The records of one hundred and sixty-one children with acute epiglottitis admitted to the Royal Alexandra Hospital for Children between January 1975 and June 1984 were reviewed. Forty-five complications occurred in thirty-four patients, including five deaths. The preferred method of airway management is direct laryngoscopy and nasotracheal intubation under general anaesthesia in the presence of skilled assistance. There should be no attempt to lie the child down prior to this, nor should awake laryngoscopy be attempted, as this may precipitate a respiratory arrest. Chloramphenicol (with or without ampicillin) should be commenced after blood cultures are obtained, as 20% of the sensitivities available demonstrated resistance to ampicillin.
Related Concept Videos
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management
Streptococcal Pharyngitis
Diphtheria
Respiratory Syncytial Virus Disease