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Updated: Jun 3, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Identification and Assessment of Toxic Substances in Environmental Justice Cases
Xiaowei Xu1, Dapeng Zhang1, Jun Zhang1
1Nanjing Institute of Environmental Science, Ministry of Ecology and Environment of China, Nanjing 210042, China.
Abstract:
This study assessed heavy metal contamination in industrial solid waste (S1, S2, S3, and S4) from the Yangtze River Delta region, employing nine risk assessment methods including total content indices (e.g., Igeo, CF) and speciation indices (e.g., ICF, GCF). Four types of industrial solid waste not classified as hazardous but containing heavy metals were analyzed. Key findings revealed significant variability in risk assessments based on chemical speciation versus total content. For example, while S1, S3, and S4 exceeded background levels, S4 showed higher mobility of Pb, Cr (VI), Cu, Ni, and As despite lower overall content. Elements like Cd and Cr (VI) exhibited discrepancies between total content and speciation-based assessments due to low background values and high toxicity. Multi-element indices (DC, RI) indicated higher pollution degrees compared to speciation indices (GCF, GRI). These results underscore the need for integrating multiple assessment methods to accurately evaluate environmental risks in judicial practices.
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