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Whole-Body MRI in Children: Concepts and Controversies-AJR Expert Panel Narrative Review

Sebastian Gallo Bernal1, Sherwin S Chan2, Yoon Y Cho2

  • 1Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

AJR. American Journal of Roentgenology
|January 8, 2025
PubMed

Insights

Whole-body MRI (WBMRI) is increasingly used in pediatric patients for diverse conditions. This review details WBMRI protocols, clinical uses, and challenges for improved standardization and access in child healthcare.

Area of Science:

  • Pediatric Radiology
  • Medical Imaging

Background:

  • Whole-body MRI (WBMRI) utilization in pediatric populations has surged.
  • Clinical applications have expanded significantly over the last decade.

Purpose of the Study:

  • To provide a comprehensive review of WBMRI in pediatric patients.
  • To discuss protocols, technical aspects, clinical indications, and implementation challenges.
  • To address controversies and emerging trends in WBMRI adoption.

Main Methods:

  • Narrative review of existing literature and expert panel insights.
  • Analysis of commonalities and variations in WBMRI protocols.
  • Summary of evidence on patient benefit across applications.

Main Results:

  • WBMRI is indicated for cancer screening, staging, fever of unknown origin, rheumatologic, vascular, and neuromuscular disorders.
  • Significant variations in WBMRI protocols exist, necessitating standardization.
  • Barriers to WBMRI access, especially in resource-limited settings, are identified.

Conclusions:

  • Standardization of WBMRI protocols is crucial for consistent pediatric care.
  • Addressing access barriers is essential for equitable WBMRI utilization.
  • Further research should focus on optimizing WBMRI benefits for children.

Keywords:
cancerinflammatory arthropathiespediatricpostmortemscreeningwhole-body MRI

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