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Updated: May 11, 2026

Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
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Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice

Published on: April 15, 2014

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Mumps Myelitis-A Rare Cause of Myelitis

Kshitij Bansal1, Tanushree Chawla1, Chanchal Goyal2

  • 1Medanta, The Medicity, Gurugram, India.

The American Journal of Tropical Medicine and Hygiene
|January 8, 2025
PubMed

Insights

This case report details a rare instance of acute transverse myelitis (ATM) following mumps infection in an adult male. Prompt steroid treatment led to significant recovery, highlighting the effectiveness of this therapy for mumps-induced neurological complications.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Mumps infection can rarely lead to serious neurological complications.
  • Acute transverse myelitis (ATM) is an inflammatory condition affecting the spinal cord.

Observation:

  • A 33-year-old male presented with fever, parotid and scrotal swelling, and paraparesis post-mumps infection.
  • MRI revealed spinal cord lesions, and CSF analysis indicated pleocytosis and elevated protein with mumps antibodies.
  • The patient experienced significant motor and sensory improvement after high-dose pulse steroid treatment.

Findings:

  • Confirmed association between mumps virus infection and acute transverse myelitis in an adult.
  • Evidence suggests an autoimmune-inflammatory mechanism triggered by the mumps infection.
  • High-dose pulse steroid therapy demonstrated efficacy in treating mumps-associated ATM.

Implications:

  • Highlights the importance of considering mumps as a potential cause of ATM in adults.
  • Emphasizes the effectiveness of prompt steroid intervention for favorable neurological outcomes.
  • Underscores the need for increased awareness of neurological sequelae of mumps infection.

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