Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Masked type I wheat allergy. Relation to exercise-induced anaphylaxis.

H Kushimoto, T Aoki

    Archives of Dermatology
    |March 1, 1985
    PubMed
    Summary

    Wheat hypersensitivity can cause exercise-induced anaphylaxis and urticarial reactions. Eliminating wheat resolved symptoms, suggesting specific wheat allergens are altered during digestion.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The evaluation of corticosteroid therapy in conjunction with plasma exchange in the treatment of renal cholesterol embolic disease. A report of 5 cases.

    American journal of nephrology·2000
    Same author

    Usefulness of serum hepatocyte growth factor for the diagnosis of amyloidosis.

    Internal medicine (Tokyo, Japan)·2000
    Same author

    Usefulness of a highly sensitive urinary and serum IL-6 assay in patients with diabetic nephropathy.

    Nephron·2000
    Same author

    [Treatment by corticosteroid and plasma exchange in 5 cases of renal cholesterol embolic disease].

    Nihon Jinzo Gakkai shi·2000
    Same author

    [A case of Chinese herbs nephropathy in which the progression of renal dysfunction was slowed by steroid therapy].

    Nihon Jinzo Gakkai shi·2000
    Same author

    Two cases of Goodpasture's syndrome--clinicopathological studies and relapse.

    Nihon Jinzo Gakkai shi·1993

    Area of Science:

    • Immunology
    • Gastroenterology

    Background:

    • Type I hypersensitivity reactions to wheat can manifest in various ways, including exercise-induced anaphylaxis and urticaria.
    • Understanding the specific allergenic components of wheat and their behavior during digestion is crucial for diagnosis and management.

    Observation:

    • Six patients presented with wheat hypersensitivity, including exercise-induced anaphylaxis and urticarial reactions.
    • Dietary elimination of wheat completely resolved symptoms in all affected individuals.

    Findings:

    • Allergens derived from gluten, gliadin, and glutenin via pepsin digestion differed from those obtained by simple extraction.
    • Pepsin-digested allergens were more strongly associated with exercise-induced anaphylaxis.
    • Trypsin digestion eliminated all tested wheat allergens.

    Implications:

    • Wheat allergens may be modified or reinforced in the stomach by pepsin.
    • These allergens appear to be degraded in the jejunum.
    • Further research into wheat allergen processing during digestion could inform diagnostic and therapeutic strategies for wheat hypersensitivity.

    Related Experiment Videos