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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...

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Related Experiment Video

Updated: Jul 26, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

Epithelioid sarcoma. Report of a case.

M L Puissegur-Lupo, W J Perret, L E Millikan

    Archives of Dermatology
    |March 1, 1985
    PubMed
    Summary

    Epithelioid sarcoma, a rare cancer, often appears as a skin mass, confusing dermatologists. Early recognition by physicians is crucial for accurate diagnosis and to prevent severe patient outcomes.

    Area of Science:

    • Orthopedic Oncology
    • Dermatopathology

    Background:

    • Epithelioid sarcoma is a rare malignant neoplasm often presenting as a subcutaneous mass.
    • It is frequently encountered by orthopedic surgeons but less recognized by dermatologists.

    Observation:

    • The presentation of epithelioid sarcoma can mimic benign conditions like nodular fasciitis or tenosynovitis.
    • Subcutaneous presentation with epidermal changes may lead to initial dermatologic evaluation.

    Findings:

    • Histopathologic interpretation of biopsy specimens can be challenging.
    • Considering epithelioid sarcoma in the differential diagnosis is vital for accurate pathological assessment.

    Implications:

    • Early and accurate diagnosis of epithelioid sarcoma can significantly reduce patient morbidity.

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  • Increased awareness among dermatologists can improve diagnostic timelines and patient outcomes.