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A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Severe heat stroke with multiorgan failure following collapse in a sauna
William Jack McIver1, Muhammad Zia2
1Accident and Emergency, Birmingham Heartlands Hospital, Birmingham, UK william.mciver3@nhs.net.
Abstract:
Heat stroke is characterised by hyperthermia and acute encephalopathy. We describe a rare case of classical heat stroke secondary to prolonged sauna use with multiorgan sequelae including seizures, liver injury, kidney injury, disseminated intravascular coagulation, rhabdomyolysis and type 2 myocardial infarction. The patient was treated with external cooling, intravenous fluid therapy and blood products, and made a full recovery without need for advanced organ support. We discuss the evidence base surrounding the immediate treatment of heat stroke in the emergency department.
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