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When a NeF Is Not Enough: Improving Assays in C3 Glomerulopathy

Pietro Canetta1

  • 1Division of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.

Journal of the American Society of Nephrology : JASN
|January 8, 2025
PubMed
Summary

No abstract available in PubMed .

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Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
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