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Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

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Published on: January 21, 2020

Relationship between periodontitis and systemic diseases: A bibliometric and visual study.

Gaetano Isola¹, Alessandro Polizzi¹, Sara Serra¹

¹Department of General Surgery and Medical-Surgical Specialities, Unit of Periodontology, University of Catania, Catania, Italy.

Periodontology 2000

|January 8, 2025

Summary

This bibliometric analysis shows a significant increase in research on periodontitis and systemic diseases, with a growing trend in publications over the last five years. Key associations include nutritional, metabolic, cardiovascular, and musculoskeletal diseases, highlighting public health challenges.

Keywords:

CiteSpace association bibliometric analysis clinical trials correlation co‐occurrence mapping host response inflammation microbiota periodontitis review systemic diseases

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Area of Science:

Periodontology
Bibliometrics
Public Health

Background:

Periodontitis is increasingly recognized for its association with various systemic diseases.
Understanding the research landscape of this relationship is crucial for public health.
Bibliometric analysis provides a comprehensive mapping of scientific literature.

Purpose of the Study:

To map and analyze observational studies on periodontitis and systemic diseases.
To identify trends, key research areas, and influential publications.
To provide an updated overview of the scientific output in this field.

Main Methods:

Bibliometric and visual analysis of records from the Web of Science database (1989-2024).
Inclusion of 1519 studies categorized using Medical Subject Headings (MeSH).
Analysis techniques included keyword co-occurrence, co-authorship, bibliographic coupling, and co-citation.

Main Results:

A significant increase in publications, with 46.73% published in the last 5 years, peaking in 2023.
Most associated systemic diseases include Nutritional & Metabolic Diseases, Cardiovascular Diseases, and Musculoskeletal Diseases.
Top contributing countries were USA, China, Brazil, and Sweden; leading journals included Journal of Periodontology and Journal of Clinical Periodontology.

Conclusions:

There is a growing trend in observational studies linking periodontitis to systemic conditions.
Periodontitis negatively impacts numerous systemic health areas, indicating rising translational research interest.
Addressing periodontitis is vital for public health, especially with an aging population, necessitating improved knowledge and care strategies.