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Mapping the research landscape of microRNAs in pain: a comprehensive bibliometric analysis

Huaiming Wang1,2, Qin Li2, Jiang Zou3

  • 1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.

Frontiers in Molecular Neuroscience
|January 8, 2025
PubMed
Abstract

Insights

MicroRNAs (miRNAs) show promise in pain medicine. This bibliometric analysis reveals a rapid growth in research, with "expression," "neuropathic pain," and "microRNAs" as key terms.

Area of Science:

  • Biomedical research
  • Pain medicine
  • Molecular biology

Background:

  • MicroRNAs (miRNAs) are increasingly recognized for their potential in pain medicine, impacting mechanisms, diagnosis, and therapy.
  • Despite growing interest, a quantitative summary of research progress in this field was lacking.

Purpose of the Study:

  • To conduct a bibliometric analysis of research on microRNAs in pain medicine.
  • To identify trends, key players, and prevalent themes in the field.

Main Methods:

  • A comprehensive literature search was performed on the Web of Science Core Collection.
  • 1,295 papers published between 2000 and 2023 were analyzed using R software, VOSviewer, and CiteSpace.

Main Results:

  • Research publications on miRNAs and pain have shown a consistent annual increase since 2000.
  • China, the United States, and Germany are the leading countries in publications.
  • Key terms include "expression," "neuropathic pain," and "microRNAs," indicating a focus on molecular mechanisms and specific pain conditions.

Conclusions:

  • The field of microRNAs in pain medicine has experienced significant growth over the past two decades.
  • While research is expanding, there is a need for more high-impact basic studies and clinical trials published in prestigious journals.
Keywords:
Web of Sciencebibliometric analysismiRNAmicroRNApain

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