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Updated: Jun 3, 2025

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
Published on: February 3, 2016
Gut Neuropathies and Intestinal Motility Disorders
David A Wattchow1,2,3, Simon J H Brookes1, Nick J Spencer1
1College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Background:
The enteric nervous system plays a key role in the coordination of gastrointestinal motility together with sympathetic, parasympathetic, and extrinsic sensory pathways. In some cases, abnormalities in neural activity in these pathways contribute to disorders of gut motility. Where this is associated with damage or death of enteric neurons, usually detected by microscopy, this is considered a gut neuropathy.
Purpose:
This review summarizes recent advances in the identification of neuropathies in a range of gastrointestinal motility disorders.
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